They truly are the Richard Burton and Elizabeth Taylor of our time.

Brangelina no more: Angelina Jolie files for divorce from Brad Pitt

Hollywood power couple Angelina Jolie and Brad Pitt is no more.

Oscar-winning actress and director Jolie, who is also a special envoy for the United Nations Refugee Agency (UNHCR), has filed for divorce from actor and producer Pitt, according to Robert Offer, lawyer for Jolie.

Offer said the decision was made “for the health of the family.”

Jolie would “not be commenting at this time” and asked that her family be “given their privacy,” he added.

In a statement issued to People magazine, Pitt also asked for privacy.

“I am very saddened by this, but what matters most now is the well-being of our kids,” Pitt said in the statement.

“I kindly ask the press to give them the space they deserve during this challenging time.”

Jolie and Pitt, referred to in entertainment media as Brangelina, have six children: Maddox, Zahara, Shiloh, Pax, Vivienne and Knox.

The two met on the set of the 2004 film Mr. and Mrs. Smith — an action comedy in which they starred as married assassins working for rival agencies — and officially became a couple in 2005.

After about a decade together, the pair married in August 2014.

Most recently, the two starred as a troubled married couple in 2015’s By the Sea, which Jolie directed.

Jolie was previously married to actor Billy Bob Thornton and, earlier, actor Johnny Lee Miller. Pitt was previously married to actress Jennifer Aniston.

Jolie and Pitt’s relationship was one of contemporary Hollywood’s most high-profile, tabloid-covered pairings.

Myriad articles debated whether they first hooked up while he was still married to Aniston, media around the world reported on the births of the globe-trotting couple’s children (Shiloh, Knox and Vivienne) and their adoptions (Maddox, Zahara and Pax), while their alleged marital spats were regular fodder in U.S. tabloids.

In recent years, Jolie has balanced her filmmaking with various causes, including working with the UN to highlight the plight of refugees and for increased awareness of breast and ovarian cancer, after her revelation that she had undergone a preventive double mastectomy (and, later, further preventive surgery).

They famously turned ravenous interest for the first images of their newborn daughter Shiloh into a philanthropic opportunity: after selling the exclusive photo and story rights to People and Hello! magazines, they donated all the proceeds to charity. They later repeated the practice, including upon the birth of twins Vivienne and Knox.

“It was extremely revolutionary that they donated the funds from the photos of their [biological children’s births] and their wedding to charities. I think that it led the way for other celebrity couples to actually do the same… That they contributed those funds to causes that really made a difference in the world was exemplary,” Natasha Koifman, president of public relations firm NKPR and board member of the charity Artists for Peace and Justice, told CBC News.

“They were the Richard Burton and Elizabeth Taylor of our time, for sure,” she said.

Jolie and Pitt often travelled the world with their children for their various film and other projects. They shared a home in southern California, as well as an estate and vineyard in the south of France.